Sodium

Known Precautions and Warnings :

Abciximab interacts with Warfarin Sodium
Avoid this combination if possible.
Resulting In: increased bleeding tendencies Co-administration of Abciximab and Warfarin Sodium may increase the risk of bleeding.

Acarbose interacts with Warfarin Sodium
Monitor closely; adjust WARFARIN dose as needed.
Resulting In: increased bleeding time Acarbose may increase the anticoagulant effects of Warfarin Sodium.

Acetaminophen interacts with Amobarbital Sodium
No monitoring or adjustment appear to be necessary at regular doses.
Resulting In: liver damage Amobarbital Sodium may reduce the pharmacologic effects of Acetaminophen. Chronic use of Amobarbital Sodium may increase risk of Acetaminophen induced liver toxicity.

Acetaminophen interacts with Pentobarbital Sodium
No monitoring or adjustment appear to be necessary at regular doses.
Resulting In: liver damage Chronic use of Pentobarbital Sodium may increase risk of Acetaminophen induced liver toxicity. Pentobarbital Sodium may reduce the pharmacologic effects of Acetaminophen.

Acetaminophen interacts with Phenobarbital Sodium
No monitoring or adjustment appear to be necessary at regular doses.
Resulting In: liver damage Chronic use of Phenobarbital Sodium may increase risk of Acetaminophen induced liver toxicity. Phenobarbital Sodium may reduce the pharmacologic effects of Acetaminophen.

Acitretin interacts with Methotrexate Sodium
Avoid this combination.
Resulting In: hepatotoxicity Acitretin may increase the risk of liver toxicity from Methotrexate.

Acyclovir interacts with Phenytoin Sodium, Prompt
Monitor for change in PHENYTOIN activity when starting or stopping ACYCLOVIR. Adjust PHENYTOIN dose as needed.
Acyclovir may reduce the serum levels and pharmacological effects of Phenytoin.

Adalimumab interacts with Methotrexate Sodium
No adjustment needed.
Methotrexate Sodium may reduce the clearance of Adalimumab.

Alendronate Sodium interacts with Aspirin
Use this combination with caution.
Resulting In: Gastrointestinal effects Concomitant use of Alendronate Sodium and Aspirin can potentiate some adverse effects.

Amobarbital Sodium interacts with Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Amobarbital Sodium can reduce the effectivness of Norgestrel.

Antithrombin III (Human) interacts with Heparin Sodium
Reduce the dose of HEPARIN during treatment with ANTITHROMBIN III.
Resulting In: bleeding Antithrombin III (Human) may increase the anticoagulant effects of Heparin Sodium.

Aprepitant interacts with Methylprednisolone Sodium Succinate
Reduce dose of IV methylprednisolone by 25%
Aprepitant may increase serum levels of Methylprednisolone Sodium Succinate.

Aprepitant interacts with Warfarin Sodium
Monitor the INR carefully for 2 weeks, particularly at 7 to 10 days, following initiation of the 3 day regimen of Emend.
Aprepitant can reduce the anticoagulant effects of Warfarin Sodium.

Argatroban interacts with Heparin Sodium
Allow sufficient time for HEPARIN'S effect on the clotting (PTT) time to decrease before initiation of ARGATROBAN therapy.
Resulting In: increased bleeding time Co-administration of Argatroban and Heparin Sodium may increase the risk of bleeding.

Ascorbic Acid interacts with Warfarin Sodium
No changes necessary except when patient is taking a large dose (>5gm/day) of ACCORBIC ACID.
Ascorbic Acid can reduce the anticoagulant effects of Warfarin Sodium.

Asparaginase interacts with Methotrexate Sodium
Do not use methotrexate with or following ASPARAGINASE treatment.
Asparaginase may reduce the pharmacologic effects of Methotrexate.

Auranofin interacts with Phenytoin Sodium, Prompt
More studies are needed to determine the significance of this interaction.
Auranofin may increase serum levels of Phenytoin.

Azathioprine interacts with Methotrexate Sodium
May require a lower THIOPURINE dose when METHOTREXATE is added to treatment regimen.
Methotrexate may increase the pharmacological effects of Azathioprine.

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Desogestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Desogestrel may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Drosperinone
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Drosperinone may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Ethynodiol Diacetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Ethynodiol Diacetate may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Levonorgestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Levonorgestrel may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Norethindrone
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norethindrone may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Norethindrone Acetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norethindrone Acetate may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Norgestimate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norgestimate may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Ethinyl Estradiol/Norgestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norgestrel may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate interacts with Fluconazole
Monitor patient for adverse effects and reduce CORTICOSTEROIDS as needed.
Azole antifungals may enhance the pharmacological and toxic effects of Corticosteroids.

Betamethasone Sodium Phosphate interacts with Itraconazole
Monitor patient for adverse effects and reduce CORTICOSTEROIDS as needed.
Azole antifungals may enhance the pharmacological and toxic effects of Corticosteroids.

Betamethasone Sodium Phosphate interacts with Ketoconazole
Monitor patient for adverse effects and reduce CORTICOSTEROIDS as needed.
Azole antifungals may enhance the pharmacological and toxic effects of Corticosteroids.

Betamethasone Sodium Phosphate interacts with Miconazole Nitrate
Monitor patient for adverse effects and reduce CORTICOSTEROIDS as needed.
Azole antifungals may enhance the pharmacological and toxic effects of Corticosteroids.

Betamethasone Sodium Phosphate interacts with Norethindrone Acetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not affect the pharmacokinetics of budesonide.)
Norethindrone Acetate may increase the pharmacologic and toxic effects of Betamethasone Sodium Phosphate

Bicalutamide interacts with Warfarin Sodium
Monitor prothrombin time and adjust WARFARIN dose as needed.
Bicalutamide may reduce the effectivness of Warfarin Sodium.

Bleomycin Sulfate interacts with Phenytoin Sodium, Prompt
Monitor serum PHENYTOIN levels and adjust dose of PHENYTOIN as necessary.
Bleomycin Sulfate may reduce the serum levels and pharmacological effects of Phenytoin.

Buprenorphine HCl interacts with Methohexital Sodium
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Buprenorphine HCl may increase the pharmacological effects of Methohexital Sodium.

Buprenorphine HCl interacts with Thiopental Sodium
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Buprenorphine HCl may increase the pharmacological effects of Thiopental Sodium.

Butabarbital Sodium interacts with Acetaminophen
No monitoring or adjustment appear to be necessary at regular doses.
Resulting In: liver damage Butabarbital Sodium may reduce the pharmacologic effects of Acetaminophen. Chronic use of Butabarbital Sodium may increase risk of Acetaminophen induced liver toxicity.

Butabarbital Sodium interacts with Ethinyl Estradiol/Desogestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Desogestrel.

Butabarbital Sodium interacts with Ethinyl Estradiol/Drosperinone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Butabarbital Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Butabarbital Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Butabarbital Sodium interacts with Ethinyl Estradiol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Butabarbital Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Butabarbital Sodium interacts with Ethinyl Estradiol/Norgestimate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Butabarbital Sodium interacts with Ethinyl Estradiol/Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Butabarbital Sodium interacts with Mestranol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Mestranol/Norethindrone.

Butabarbital Sodium interacts with Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Norethindrone Acetate.

Butabarbital Sodium interacts with Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Butabarbital Sodium can reduce the effectivness of Norgestrel.

Butorphanol Tartrate interacts with Methohexital Sodium
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Butorphanol Tartrate may increase the pharmacological effects of Methohexital Sodium.

Butorphanol Tartrate interacts with Thiopental Sodium
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Butorphanol Tartrate may increase the pharmacological effects of Thiopental Sodium.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Carbenicillin Indanyl Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Carbenicillin Indanyl Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Mestranol/Norethindrone.

Carbenicillin Indanyl Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Norethindrone Acetate.

Carbenicillin Indanyl Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Carbenicillin Indanyl Sodium can reduce the effectivness of Norgestrel.

Carboplatin interacts with Phenytoin Sodium, Prompt
Monitor PHENYTOIN levels and adjust dose as necessary.
Carboplatin may reduce the serum levels and pharmacological effects of Phenytoin.

Carboplatin interacts with Warfarin Sodium
Carefully monitor anticoagulant factors during and after CARBOPLATIN therapy. Adjust WARFARIN dose as necessary.
Resulting In: increased bleeding tendencies Carboplatin may increase the anticoagulant effects of Warfarin Sodium.

Carmustine interacts with Phenytoin Sodium, Prompt
Monitor serum PHENYTOIN levels and adjust dose of PHENYTOIN as necessary.
Carmustine may reduce the serum levels and pharmacological effects of Phenytoin.

Cephalothin Sdoium interacts with Colistimethate Sodium
Monitor renal functions. Discontinue COLISTIMETHATE if interaction occurs.
Resulting In: renal dysfunction Concomitant use of Cephalothin Sodium and Colistimethate Sodium can potentiate some adverse effects.

Cerivastatin Sodium interacts with Gemfibrozil
Avoid combining CERIVASTATIN and GEMFIBROZIL. If the combination of gemifibrozil and a statin is needed in patients with severe hyperlipidemia (goal of lowering LDL-C and TG) use one of the others..Lescol, Lipitor, Mevacor, Pravachol, Zocor and monitor fo
Resulting In: Rhabdomyolysis, Myopathy Gemfibrozil can increase the serum levels of Cerivastatin Sodium and increase the risk of toxicity.

Cerivastatin Sodium interacts with Nefazodone HCl
Ask patient to report any unexplained muscle weakness, pain or tenderness. Fluvastatin or Pravastatin may be safer alternatives.
Resulting In: Polymyositis, Rhabdomyolysis Nefazodone HCl can increase the serum levels of Cerivastatin Sodium and increase the risk of toxicity.

Chloral Hydrate interacts with Warfarin Sodium
No adjustments appear to be necessary. Monitor prothrombin levels.
Chloral Hydrate can increase the anticoagulant effects of Warfarin Sodium.

Chloroquine interacts with Methotrexate Sodium
Observe the patient for clinical response. Increase dose of METHOTREXATE if necessary.
Chloroquine may reduce the antirheumatic effect of Methotrexate.

Cidofovir interacts with Foscarnet Sodium
Avoid concomitant use of CIDOFOVIR other nephrotoxic drugs. Discontinue nephrotoxic agents 7 days prior to CIDOFOVIR therapy.
Resulting In: nephrotoxicity Concurrent use of Cidofovir with Foscarnet Sodium can increase toxicity of organ systems.

Ciprofloxacin HCl interacts with Warfarin Sodium
Monitor anticoagulation factors more frequently especially when adding or discontinuing QUINOLONES. Levofloxacin may be a safer alternative.
Resulting In: increased bleeding tendencies Ciprofloxacin HCl can increase the anticoagulant effects of Warfarin Sodium.

Cisapride interacts with Warfarin Sodium
Monitor anticoagulant function when CISAPRIDE is started, stopped or changed in dosage. Adjust the dose of WARFARIN as necessary.
Resulting In: increased bleeding tendencies Cisapride can increase the anticoagulant effects of Warfarin Sodium.

Cisplatin interacts with Phenytoin Sodium, Prompt
Monitor serum PHENYTOIN levels and adjust dose of PHENYTOIN as necessary.
Cisplatin may reduce the serum levels and pharmacological effects of Phenytoin.

Clopidogrel interacts with Warfarin Sodium
Monitor bleeding time and use with caution.
Resulting In: increased bleeding time Clopidogrel may increase the anticoagulant effects of Warfarin Sodium.

Cloxacillin Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Cloxacillin Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Cloxacillin Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Mestranol/Norethindrone.

Cloxacillin Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Norethindrone Acetate.

Cloxacillin Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Cloxacillin Sodium can reduce the effectivness of Norgestrel.

Coenzyme Q10 interacts with Warfarin Sodium
Monitor INR carefully.
Coenzyme Q10 can reduce the effectivness of Warfarin Sodium.

Cyclophosphamide interacts with Methotrexate Sodium
Alteration in the effects of either drugs unlikely. Do usual monitoring.
Effects of Methotrexate on Cyclophosphamide are variable.

Cyclophosphamide interacts with Warfarin Sodium
Carefully monitor anticoagulant factors during and after CYCLOPHOSPHAMIDE therapy. Adjust WARFARIN dose as necessary.
Resulting In: increased bleeding tendencies Cyclophosphamide may increase the anticoagulant effects of Warfarin Sodium.

Cyclosporine interacts with Ceftriaxone Sodium
Monitor CYCLOSPORINE and creatinine levels and adjust dose of CYCLOSPORINE as necessesary.
Resulting In: Cyclosporine toxicity Ceftriaxone Sodium can increase the serum levels of Cyclosporine and increase the risk of toxicity.

Cyclosporine interacts with Nafcillin Sodium
Manage: Consider giving an alternative antibiotic for NAFCILLIN in the treatment of, or prophylaxis against, staphylococcal infection in patients receiving CYCLOSPORINE.
Nafcillin Sodium may increase or decrease blood levels of Cyclosporine.

Dicloxacillin Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Dicloxacillin Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Dicloxacillin Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Mestranol/Norethindrone.

Dicloxacillin Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Norethindrone Acetate.

Dicloxacillin Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Dicloxacillin Sodium can reduce the effectivness of Norgestrel.

Docusate Sodium interacts with Mineral Oil
Use of MINERAL OIL with DOCUSATE is not recommended.
Docusate Sodium may increase the absorption of Mineral Oil.

Doxycycline interacts with Methotrexate Sodium
Monitor METHOTREXATE level and watch for signs of toxicity.
Resulting In: bone marrow suppression Doxycycline can increase the serum levels of Methotrexate and increase the risk of toxicity.

Epoprostenol Sodium interacts with Aspirin
Monitor anticoagulant activity and signs of bleeding. Adjust therapy as needed.
Resulting In: increased bleeding tendencies Co-administration of Epoprostenol Sodium and Aspirin may increase the risk of bleeding.

Eptifibatide interacts with Heparin Sodium
Monitor for signs of bleeding and use with caution.
Resulting In: increased bleeding tendencies Co-administration of Eptifibatide and Heparin Sodium may increase the risk of bleeding.

Ertapenem Sodium interacts with Probenecid
Monitor pharmacological effects and make adjustment if necessary.
Probenecid may reduce the clearance, prolong the half-life and increase the serum levels of Ertapenem Sodium.

Estramustine Phosphate Sodium interacts with Aldesleukin
Avoid this combination.
Concurrent use of Aldesleukin with Estramustine Phosphate Sodium can increase toxicity of organ systems.

Ethacrynic Acid interacts with Warfarin Sodium
Monitor anticoagulant activity. A lower dose of ANTICOAGULANT may be required.
Ethacrynic Acid may increase the anticoagulant effects of Warfarin Sodium.

Ethinyl Estradiol/Etonogestrel interacts with Carbenicillin Indanyl Sodium
Use of additional contraceptive method is advisable.
Carbenicillin Indanyl Sodium can reduce the effectivness of Ethinyl Estradiol/Etonogestrel.

Ethinyl Estradiol/Etonogestrel interacts with Cloxacillin Sodium
Use of additional contraceptive method is advisable.
Cloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Etonogestrel.

Ethinyl Estradiol/Etonogestrel interacts with Dicloxacillin Sodium
Use of additional contraceptive method is advisable.
Dicloxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Etonogestrel.

Ethinyl Estradiol/Etonogestrel interacts with Nafcillin Sodium
Use of additional contraceptive method is advisable.
Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Etonogestrel.

Ethinyl Estradiol/Etonogestrel interacts with Oxacillin Sodium
Use of additional contraceptive method is advisable.
Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Etonogestrel.

Etidronate Disodium interacts with Warfarin Sodium
Not clinically significant. Monitor prothrombin time as usual.
Etidronate Disodium can increase the anticoagulant effects of Warfarin Sodium.

Etoposide interacts with Warfarin Sodium
Carefully monitor anticoagulant factors during and after chemotherapy. Adjust WARFARIN dose as necessary.
Resulting In: increased bleeding tendencies Etoposide may increase the anticoagulant effects of Warfarin Sodium.

Etretinate interacts with Warfarin Sodium
Monitor anticoagulant activity and adjust WARFARIN dose as needed.
Etretinate can reduce the anticoagulant effects of Warfarin Sodium.

Felbamate interacts with Warfarin Sodium
Monitor anticoagulant activity and adjust the dose of WARFARIN as needed.
Felbamate may increase the anticoagulant effects of Warfarin Sodium.

Feverfew interacts with Warfarin Sodium
Carefully monitor PT and INR but avoid this combination if possible.
Concomitant use of Feverfew and Warfarin Sodium can potentiate some adverse effects.

Fluorouracil interacts with Warfarin Sodium
Carefully monitor anticoagulant factors during and after chemotherapy. Adjust WARFARIN dose as necessary.
Resulting In: increased bleeding tendencies Fluorouracil may increase the anticoagulant effects of Warfarin Sodium.

Flurbiprofen Sodium interacts with Acetylcholine Chloride
No adjustments appear to be necessary. More studies are needed to document the existence and significance of this interaction.
Flurbiprofen Sodium can reduce the effectivness of Acetylcholine Chloride.

Flurbiprofen Sodium interacts with Carbachol
More studies are neede to document the existence and significance of this interaction.
Flurbiprofen Sodium can reduce the effectivness of Carbachol.

Flutamide interacts with Warfarin Sodium
Monitor prothrombin time and adjust WARFARIN dose as needed.
Flutamide may increase the anticoagulant effects of Warfarin Sodium.

Fluvastatin interacts with Warfarin Sodium
Monitor anticoagulation factors when starting or stopping HMG-CoA REDUCTASE INHIBITOR. Atorvastatin, Cerivastatin and Pravastatin do not seem to interact with WARFARIN.
Fluvastatin can increase the anticoagulant effects of Warfarin Sodium.

Foscarnet Sodium interacts with Cyclosporine
Monitor renal function. It may become necessary to discontinue FISCARNET treatment and manage the patient as needed.
Resulting In: nephrotoxicity Combination of Foscarnet Sodium and Cyclosporine may increase risk of renal failure.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Desogestrel
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Desogestrel.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Drosperinone
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Norethindrone
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Norgestimate
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Fosphenytoin Sodium interacts with Ethinyl Estradiol/Norgestrel
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Fosphenytoin Sodium interacts with Mestranol/Norethindrone
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Mestranol/Norethindrone.

Fosphenytoin Sodium interacts with Norethindrone Acetate
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Norethindrone Acetate.

Fosphenytoin Sodium interacts with Norgestrel
Titrate ORAL CONTRACEPTIVE dose or use an alternate contraceptive method when patient is on HYDANTOIN therapy.
Resulting In: contraceptive failure Fosphenytoin Sodium can reduce the effectivness of Norgestrel.

Furosemide interacts with Phenytoin Sodium, Prompt
Monitor patient response; may need to increase FUROSEMIDE dose.
Phenytoin may decrease the diuretic effects of Furosemide.

Furosemide interacts with Warfarin Sodium
Monitor anticoagulant activity. A lower dose of ANTICOAGULANT may be required.
Furosemide may increase the anticoagulant effects of Warfarin Sodium.

Ganciclovir interacts with Imipenem/Cilastatin Sodium
Do not use together unless the potential benefits outweigh risks.
Resulting In: seizures Concomitant use of Ganciclovir and Imipenem/Cilastatin Sodium can potentiate some adverse effects.

Garlic interacts with Warfarin Sodium
Monitor INR and prothrombin times carefully.
Concomitant use of Garlic and Warfarin Sodium can potentiate some adverse effects.

Gefitinib interacts with Warfarin Sodium
Monitor regularly for changes in prothrombin time or INR.
Resulting In: bleeding Co-administration of Gefitinib and Warfarin Sodium may increase the risk of bleeding.

Ginseng interacts with Warfarin Sodium
Avoid combination if possible. If combination is needed, monitor anticoagulant factors and adjust dose of WARFARIN as necessary.
Ginseng can reduce the anticoagulant effects of Warfarin Sodium.

Glucagon interacts with Warfarin Sodium
Monitor anticoagulant activity and signs of bleeding. Adjust dose of each drug as needed.
Resulting In: increased bleeding tendencies Glucagon can increase the anticoagulant effects of Warfarin Sodium.

Glutethimide interacts with Warfarin Sodium
Monitor anticoagulant activity and prothrombin time. Adjust the dose of COUMARIN ANTICOAGULANT if needed. Consider using an alternative sedative such as Benzodiazepines.
Glutethimide may inhibit the pharmacological action of Warfarin Sodium.

Gold Sodium Thiomalate interacts with Penicillamine
Do not take them together.
Gold Sodium Thiomalate is contraindicated with Penicillamine.

Grape seed extract interacts with Warfarin Sodium
Use with caution. Monitor INR carefully.
Grape seed extract can increase the anticoagulant effects of Warfarin Sodium.

Griseofulvin interacts with Warfarin Sodium
Monitor anticoagulant activity and adjust WARFARIN dose as needed when using this combination.
Griseofulvin can reduce the anticoagulant effects of Warfarin Sodium.

Hawthorn interacts with Sodium Nitrite
Increased vasodilation may occur. Monitor blood pressure and adjust dosage as needed.
Resulting In: vasodilation Combination of Hawthorn and Sodium Nitrite may potentiate the effects of Sodium Nitrite.

Heparin Sodium interacts with Aspirin
Monitor patient for signs of bleeding and adjust therapy as needed.
Resulting In: increased bleeding tendencies Co-administration of Aspirin and Heparin Sodium may increase the risk of bleeding.

Heparin Sodium interacts with Nitroglycerin
Monitor coagulation factors when using this drug combination. Adjust the dose of HEPARIN accordingly.
Nitroglycerin may reduce the pharmacologic effects of Heparin Sodium.

Heparin Sodium interacts with Streptokinase
Monitor coagulation factors and titrate HEPARIN dose accordingly.
Streptokinase can reduce the anticoagulant effects of Heparin Sodium.

Hydroxychloroquine Sulfate interacts with Methotrexate Sodium
Observe the patient for clinical response. Increase dose of METHOTREXATE if necessary.
Hydroxychloroquine Sulfate may reduce the antirheumatic effect of Methotrexate.

Ifosfamide interacts with Warfarin Sodium
Monitor prothrombin time when starting or stopping IFOSFAMIDE. Adjust WARFARIN dose as needed.
Resulting In: increased bleeding tendencies Ifosfamide may increase the anticoagulant effects of Warfarin Sodium.

Imatinib mesylate interacts with Warfarin Sodium
Patients who require anticoagulation should receive low-molecular weight or standard heparin if possible. If warfarin is preferred, then monitor INR/PT carefully and adjust dose accordingly.
Imatinib mesylate can increase the anticoagulant effects of Warfarin Sodium.

Influenza Virus Vaccine interacts with Warfarin Sodium
No special precautions necessary. This interaction may occur in a small number of patients.
Influenza Virus Vaccine may increase the anticoagulant effects of Warfarin Sodium.

Isoniazid interacts with Warfarin Sodium
Monitor prothrombin time and adjust WARFARIN dose as needed.
Resulting In: increased bleeding tendencies Isoniazid may increase the anticoagulant effects of Warfarin Sodium.

Leflunomide interacts with Methotrexate Sodium
Monitor liver functions. Elevations of liver enzymes usually resolve after disconitnuation of LEFLUNOMIDE.
Resulting In: abnormal liver function tests Leflunomide may increase the risk of liver toxicity from Methotrexate.

Leflunomide interacts with Warfarin Sodium
Check INR a few days after warfarin patients start Arava
Leflunomide can increase the anticoagulant effects of Warfarin Sodium.

Leucovorin Calcium interacts with Methotrexate Sodium
High doses LEUCOVORIN may reduce the efficacy of intrathecally administered METHOTREXATE. Monitor patient response and adjust therapy if encessary.
Leucovorin Calcium can reduce the effectivness of Methotrexate.

Leucovorin Calcium interacts with Phenytoin Sodium, Prompt
Monitor for increased seizure frequency in susceptible children. Be aware of this potential interaction.
Resulting In: Seizures Folic acid in large amounts may counteract the antiepileptic effect of Phenytoin.

Levamisole HCl interacts with Phenytoin Sodium, Prompt
This is a 3 drug interaction with LEVAMISOLE, FLUOROURACIL and PHENYTOIN. PHENDYTOIN dose may need to be lowered.
Levamisole HCl may increase serum levels of Phenytoin.

Levamisole HCl interacts with Warfarin Sodium
Monitor anticoagulation parameters when starting or stopping LEVAMISOLE. Adjust WARFARIN dose as needed.
Levamisole HCl may increase the anticoagulant effects of Warfarin Sodium.

Levobupivacaine interacts with Phenytoin Sodium, Prompt
Monitor for patient response. May require a higher dose of LEVOBUPIVACAINE.
Phenytoin may increase the metabolism of Levobupivacaine and decrease its serum concentration.

Levothyroxine Sodium (T4) interacts with Aluminum Hydroxide
Consider monitoring TSH levels.
Aluminum Hydroxide may increase the serum levels of thyroid stimulating hormone (TSH). Aluminum Hydroxide may reduce the pharmacologic effects of Levothyroxine Sodium.

Levothyroxine Sodium (T4) interacts with Iron
Separate the administration times as much as possible. Monitor thyroid function and adjust the dose of LEVOTHYROXINE as needed.
Resulting In: hypothyroidism Iron can reduce the absorption of Levothyroxine Sodium. Iron may reduce the pharmacologic effects of Levothyroxine Sodium.

Levothyroxine Sodium (T4) interacts with Lovastatin
Monitor patient response to THYROID when LOVASTATIN is started or stopped.
Lovastatin may increase or decrease effectivness of Levothyroxine Sodium.

Levothyroxine Sodium (T4) interacts with Sucralfate
Separate administration time by at least 8 hours; may need to increase the dose of LEVOTHYROXINE.
Sucralfate may reduce the pharmacologic effects of Levothyroxine Sodium.

Lovastatin interacts with Warfarin Sodium
Monitor anticoagulation factors when starting or stopping HMG-CoA REDUCTASE INHIBITOR. Atorvastatin, Cerivastatin and Pravastatin do not seem to interact with WARFARIN.
Lovastatin can increase the anticoagulant effects of Warfarin Sodium.

Mebendazole interacts with Phenytoin Sodium, Prompt
Monitor MEBENDAZOLE level and adjust dose as needed. May need to increase MEBENDAZOLE dose for patients taking this drug combination.
Phenytoin may reduce the pharmacologic effects of Mebendazole.

Mercaptopurine interacts with Methotrexate Sodium
May require a lower THIOPURINE dose when METHOTREXATE is added to treatment regimen.
Methotrexate may increase the pharmacological effects of Mercaptopurine.

Mesalamine interacts with Warfarin Sodium
Monitor anticoagulant activity when starting chamging or stopping MESALAMINE. May need to discontinue MESALAMINE if interaction occurs.
Mesalamine can reduce the anticoagulant effects of Warfarin Sodium.

Methohexital Sodium interacts with Hydrocodone Bitartrate
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Hydrocodone Bitartrate may increase the pharmacological effects of Methohexital Sodium.

Methohexital Sodium interacts with Nalbuphine
No special precautions, just routine monitoring in anesthesia.
Resulting In: Apnea Nalbuphine may increase the pharmacological effects of Methohexital Sodium.

Methotrexate Sodium interacts with Aldesleukin
Avoid this combination.
Concurrent use of Aldesleukin with Methotrexate can increase toxicity of organ systems.

Methotrexate Sodium interacts with Amiodarone HCl
Monitor for signs of METHOTREXATE toxicity when starting AMIODARONE.
Resulting In: Methotrexate toxicity Concomitant administartion of Amiodarone HCl and Methotrexate may increase the risk of Methotrexate toxicity.

Methotrexate Sodium interacts with Charcoal, Activated
Do not administer them at the same time.
Charcoal, Activated can reduce the absorption of Methotrexate.

Methotrexate Sodium interacts with Digoxin
Monitor serum DIGOXIN level and patient response. Adjust DIGOXIN dosage if needed.
Methotrexate can reduce the absorption of Digoxin. Methotrexate may reduce the serum levels and pharmacological effects of Digoxin.

Methotrexate Sodium interacts with Etretinate
Monitor METHOTREXATE level and decrease its dose as needed.
Resulting In: Methotrexate toxicity Etretinate may increase the pharmacologic and toxic effects of Methotrexate

Methotrexate Sodium interacts with Omeprazole
Stop OMEPRAZOLE a few days before METHOTREXATE therapy. Consider using an alternative therapy such as Cimetidine, Ranitidine instead of OMEPRAZOLE.
Resulting In: Methotrexate toxicity Omeprazole can increase the serum levels of Methotrexate and increase the risk of toxicity.

Methotrexate Sodium interacts with Phenytoin Sodium, Prompt
Monitor serum PHENYTOIN levels and adjust dose of PHENYTOIN as necessary.
Methotrexate may reduce the serum levels and pharmacological effects of Phenytoin.

Methotrexate Sodium interacts with Probenecid
Monitor METHOTREXATE level and adjust dose as needed. May need to lower METHOTREXATE dose or require longer Leucovorin rescue treatment.
Resulting In: Methotrexate toxicity Probenecid may increase the serum levels and pharmacological and adverse effects of Methotrexate.

Methotrexate Sodium interacts with Procarbazine HCl
Allow at least 72 hours between the last dose of PROCARBAZINE and the initiation of a high-dose METHOTREXATE.
Resulting In: nephrotoxicity Procarbazine HCl may increase the risk of Methotrexate induced nephrotoxicity.

Modafinil interacts with Phenytoin Sodium, Prompt
Monitor PHENYTOIN level and signs of toxicity. Adjust therapy if needed.
Modafinil can increase the serum levels of Phenytoin and increase the risk of toxicity.

Modafinil interacts with Warfarin Sodium
Monitor anticoagulation parameters when using this drug combination.
Modafinil may alter the therapeutic effects of Warfarin Sodium.

Moricizine HCl interacts with Warfarin Sodium
Monitor prothrombin time and watch for signs of bleeding when adding or changing MORICIZINE dosage.
Resulting In: increased bleeding tendencies Moricizine HCl may increase the anticoagulant effects of Warfarin Sodium.

Nafcillin Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol.

Nafcillin Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Nafcillin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Nafcillin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Nafcillin Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Nafcillin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Nafcillin Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Nafcillin Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Nafcillin Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Mestranol/Norethindrone.

Nafcillin Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Norethindrone Acetate.

Nafcillin Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Nafcillin Sodium can reduce the effectivness of Norgestrel.

Nilutamide interacts with Phenytoin Sodium, Prompt
Monitor patient response and watch for increaed side effects to PHENYTOIN. Adjust PHENYTOIN dose as needed.
Nilutamide may reduce the clearance, prolong the half-life and increase the serum levels of Phenytoin.

Nitroprusside Sodium interacts with Clonidine
Monitor blood pressure and watch for signs of hypotension. Adjust therapy as needed.
Resulting In: Hypotension Clonidine may increase the antihypertensive effects of Nitroprusside Sodium.

Nitroprusside Sodium interacts with Diltiazem HCl
Patient stabilized on DILTIAZEM may require a lower dose of NITROPRUSSIDE to produce hypotension. Monitor blood pressure closely.
Resulting In: Hypotension Diltiazem HCl may increase the antihypertensive effects of Nitroprusside Sodium.

Norfloxacin interacts with Warfarin Sodium
Monitor anticoagulation factors more frequently especially when adding or discontinuing QUINOLONES. Levofloxacin may be a safer alternative.
Resulting In: increased bleeding tendencies Norfloxacin can increase the anticoagulant effects of Warfarin Sodium.

Ofloxacin interacts with Warfarin Sodium
Monitor anticoagulation factors more frequently especially when adding or discontinuing QUINOLONES. Levofloxacin may be a safer alternative.
Resulting In: increased bleeding tendencies Ofloxacin can increase the anticoagulant effects of Warfarin Sodium.

Olsalazine Sodium interacts with Azathioprine
Monitor hematologic functions and adjust therapy as needed.
Resulting In: Bone marrow suppression Olsalazine Sodium may increase the pharmacologic and toxic effects of Azathioprine

Olsalazine Sodium interacts with Mercaptopurine
Monitor hematologic functions and adjust therapy as needed.
Resulting In: Bone marrow suppression Olsalazine Sodium may increase the pharmacologic and toxic effects of Mercaptopurine

Omeprazole interacts with Warfarin Sodium
Monitor anticoagulation factors when adding or discontinuing WARFARIN. Adjust WARFARIN dose as needed.
Omeprazole can increase the anticoagulant effects of Warfarin Sodium.

Oxacillin Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol.

Oxacillin Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Oxacillin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Oxacillin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Oxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Oxacillin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Oxacillin Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Oxacillin Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Oxacillin Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Mestranol/Norethindrone.

Oxacillin Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Norethindrone Acetate.

Oxacillin Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Oxacillin Sodium can reduce the effectivness of Norgestrel.

Oxcarbazepine interacts with Phenytoin Sodium, Prompt
Plasma level of PHENYTOIN increased by 40% when OXCARBAZEPINE dose is greater than 1200mg/day. Monitor PHENYTOIN and OXCARBAZEPINE levels and make adjustment as needed. May need to decrease the dose of PHENYTOIN when using high dose OXCARBAZEPINE (>1200mg
Oxcarbazepine may increase serum levels of Phenytoin. Phenytoin may decrease the plasma level of the active metabolite of Oxcarbazepine.

Paroxetine HCl interacts with Phenytoin Sodium, Prompt
Monitor PHENYTOIN level and patient response. Adjust PHENYTOIN dose as needed when starting, changing or stopping PAROXETINE.
Paroxetine may reduce the serum levels and pharmacological effects of Phenytoin.

Penicillin G Sodium interacts with Ethinyl Estradiol
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol.

Penicillin G Sodium interacts with Ethinyl Estradiol/Drosperinone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Penicillin G Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Penicillin G Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Penicillin G Sodium interacts with Ethinyl Estradiol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Penicillin G Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Penicillin G Sodium interacts with Ethinyl Estradiol/Norgestimate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Penicillin G Sodium interacts with Ethinyl Estradiol/Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Penicillin G Sodium interacts with Levonorgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Levonorgestrel.

Penicillin G Sodium interacts with Mestranol/Norethindrone
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Mestranol/Norethindrone.

Penicillin G Sodium interacts with Norethindrone Acetate
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Norethindrone Acetate.

Penicillin G Sodium interacts with Norgestrel
Use of additional contraceptive method is advisable.
Resulting In: contraceptive failure Penicillin G Sodium can reduce the effectivness of Norgestrel.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Desogestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Desogestrel.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Drosperinone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Norgestimate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Pentobarbital Sodium interacts with Ethinyl Estradiol/Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Pentobarbital Sodium interacts with Mestranol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Mestranol/Norethindrone.

Pentobarbital Sodium interacts with Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Norethindrone Acetate.

Pentobarbital Sodium interacts with Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Pentobarbital Sodium can reduce the effectivness of Norgestrel.

Pentosan Polysulfate Sodium interacts with Aspirin
PENTOSAN is a weak anticoagulant, therefore this combination may increase the risk of bleeding. Use with caution.
Resulting In: Ecchymosis, Bleeding gums, epistaxis, increased bleeding tendencies Co-administration of Aspirin and Pentosan Polysulfate Sodium may increase the risk of bleeding.

Phenytoin Sodium, Prompt interacts with Chlorpheniramine Maleate
Monitor PHENYTOIN levels and observe for signs of toxicity if CHLORPHENIRAMINE is started or stopped. Adjust dose of PHENYTOIN as necessary.
Chlorpheniramine Maleate may increase the serum levels and pharmacological and adverse effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Diazoxide
Monitor PHENYTOIN level and observe patient for signs of toxicity or decreased PHENYTOIN activity. Adjust PHENYTOIN dose as needed.
Diazoxide may reduce the serum levels and pharmacological effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Dopamine HCl
Use extreme caution in this drug combination. Monitor blood pressure and discontinue PHENYTOIN if hypotension develops.
Resulting In: Cardiac arrest, Hypotension Concomitant use of Dopamine HCl and Phenytoin can potentiate some adverse effects.

Phenytoin Sodium, Prompt interacts with Imipramine HCl
Monitor PHENYTOIN level and watch for signs of toxicity. Adjust PHENYTOIN dosage as needed.
Imipramine HCl may increase the serum levels and pharmacological and adverse effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Influenza Virus Vaccine
No adjustments appear to be necessary.
Effects of Influenza Virus Vaccine on Phenytoin are variable. Influenza Virus Vaccine may increase or decrease serum levels of Phenytoin.

Phenytoin Sodium, Prompt interacts with Lithium
No special monitoring necessary. Decrease LITHIUM dose if toxicity develops.
Resulting In: Lithium toxicity Concomitant administartion of Phenytoin and Lithium may increase the risk Lithium toxicity.

Phenytoin Sodium, Prompt interacts with Loxapine HCl
Monitor PHENYTOIN level and observe patient for a decrease in PHENYTOIN activity or an increase in toxicity when adding or stopping LOXAPINE from the treatment regimen. Adjust PHENYTOIN dosage as needed.
Loxapine may reduce the serum levels and pharmacological effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Methylphenidate HCl
Monitor serum PHENYTOIN level and observing patient for PHENYTOIN toxicity or a decrease in PHENYTOIN activity when adding or stopping METHYLPHENIDATE from regimen. Adjust PHENYTOIN dose as needed.
Methylphenidate HCl may increase the serum levels and pharmacological and adverse effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Nifedipine
Monitor PHENYTOIN level and watch for signs of toxicity. Adjust PHENYTOIN dose as needed.
Nifedipine can increase the serum levels of Phenytoin and increase the risk of toxicity.

Phenytoin Sodium, Prompt interacts with Nitrofurantoin
Monitor PHENYTOIN level and observe patient for a decrease in PHENYTOIN activity or an increase in toxicity when adding or stopping NITROFURANTOIN from regimen. Adjust PHENYTOIN dose as needed.
Nitrofurantoin may reduce the serum levels and pharmacological effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Propoxyphene
No special precautions necessary.
Propoxyphene may increase serum levels of Phenytoin. Propoxyphene may increase the pharmacological effects of Phenytoin.

Phenytoin Sodium, Prompt interacts with Sucralfate
Monitor patient response and adjust PHENYTOIN dosage as needed.
Sucralfate may reduce the pharmacologic effects of Phenytoin.

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Desogestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Desogestrel may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Drosperinone
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Drosperinone may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Ethynodiol Diacetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Ethynodiol Diacetate may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Levonorgestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Levonorgestrel may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Norethindrone
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norethindrone may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Norethindrone Acetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norethindrone Acetate may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Norgestimate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norgestimate may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Ethinyl Estradiol/Norgestrel
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Ethinyl Estradiol/Norgestrel may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate interacts with Norethindrone Acetate
May need to reduce CORTICOSTEROID dose when starting ORAL CONTRACEPTIVE. (ORAL CONTRACEPTIVES do not seem to affect the pharmacokinetics of budesonide.)
Norethindrone Acetate may increase the pharmacologic and toxic effects of Prednisolone Sodium Phosphate

Probenecid interacts with Thiopental Sodium
The anesthetic dose of THIOPENTAL may be reduced. No special precautions, just routine monitoring necessary.
Probenecid may increase and prolong the pharmacological effects of Thiopental Sodium.

Profimer Sodium interacts with Allopurinol
Avoid this combination if possible.
Allopurinol can interfere with Profimer Sodium photodynamic therapy.

Profimer Sodium interacts with Dimethyl Sulfoxide
Use with caution and monitor patient response.
Dimethyl Sulfoxide may reduce the pharmacologic effects of Profimer Sodium.

Profimer Sodium interacts with Griseofulvin
Use with caution. Advise patient to avoid sunlight and bright indoor light.
Resulting In: Photosensitivity Concomitant use of Profimer Sodium and other photosensitizing agents such as Griseofulvin can increase the photosensitivity reaction.

Profimer Sodium interacts with Mannitol
Use with caution and monitor patient response.
Mannitol can interfere with Profimer Sodium photodynamic therapy.

Profimer Sodium interacts with Oxytetracycline
Use this combination with caution. Advise patient to avoid sunlight and bright indoor light.
photosensitivity Concomitant use of Profimer Sodium and other photosensitizing agents such as Oxytetracycline can increase the photosensitivity reaction.

Propoxyphene HCl interacts with Warfarin Sodium
Monitor clotting time regularly. May need to decrease the dose of WARFARIN.
Resulting In: hemorrhage Propoxyphene HCl can increase the anticoagulant effects of Warfarin Sodium.

Propranolol HCl interacts with Warfarin Sodium
No special adjustment necessary. Monitor clotting time as usual.
Propranolol HCl can increase the anticoagulant effects of Warfarin Sodium.

Quetiapine Fumarate interacts with Phenytoin Sodium, Prompt
May need a higher QUETIAPINE dose for patient taking this combination. Adjust QUETIAPINE dosage when starting, changing or stopping PHENYTOIN.
Phenytoin may increase the clearance of Quetiapine Fumarate.

Quinidine interacts with Phenytoin Sodium, Prompt
Monitor QUINIDINE level and increase QUINIDINE dose as needed.
Phenytoin may reduce the pharmacologic effects of Quinidine.

Rabeprazole Sodium interacts with Cyclosporine
Monitor CYCLOSPORINE level and make adjustments as needed.
Resulting In: Cyclosporine toxicity Rabeprazole Sodium can increase the serum levels of Cyclosporine and increase the risk of toxicity.

Rabeprazole Sodium interacts with Digoxin
Monitor DIGOXIN level and make necessary adjustments.
Rabeprazole Sodium may increase blood levels of Digoxin.

Raloxifene interacts with Levothyroxine Sodium (T4)
May cause hypothyroidism if taken together. Separate the administration of each medication by 12 hours.
Raloxifene can reduce the absorption of Levothyroxine Sodium (T4).

Raloxifene interacts with Warfarin Sodium
RALOXIFENE may decrease clotting time by 10%. Monitor coagulation time closely.
Raloxifene can reduce the anticoagulant effects of Warfarin Sodium.

Rosuvastatin interacts with Warfarin Sodium
Monitor INR carefully.
Concommitant use of Rosuvastatin and Warfarin Sodium may cause an increase in prothrombin time.

Secobarbital Sodium interacts with Ethinyl Estradiol/Desogestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Desogestrel.

Secobarbital Sodium interacts with Ethinyl Estradiol/Drosperinone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Drosperinone.

Secobarbital Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Ethynodiol Diacetate.

Secobarbital Sodium interacts with Ethinyl Estradiol/Levonorgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Levonorgestrel.

Secobarbital Sodium interacts with Ethinyl Estradiol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone.

Secobarbital Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norethindrone Acetate.

Secobarbital Sodium interacts with Ethinyl Estradiol/Norgestimate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestimate.

Secobarbital Sodium interacts with Ethinyl Estradiol/Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Ethinyl Estradiol/Norgestrel.

Secobarbital Sodium interacts with Mestranol/Norethindrone
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Mestranol/Norethindrone.

Secobarbital Sodium interacts with Norethindrone Acetate
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Norethindrone Acetate.

Secobarbital Sodium interacts with Norgestrel
Use alternative methods of contraception to avoid pregnancy.
Resulting In: contraceptive failure Secobarbital Sodium can reduce the effectivness of Norgestrel.

Simvastatin interacts with Warfarin Sodium
Monitor coagulation factors when starting or stopping HMG-CoA REDUCTASE INHIBITOR. Atorvastatin, Cerivastatin and Pravastatin do not seem to interact with WARFARIN.
Simvastatin can increase the anticoagulant effects of Warfarin Sodium.

Sodium Bicarbonate interacts with Ketoconazole
Give ANTACIDS at least 2 hours after KETOCONAZOLE.
Sodium Bicarbonate may reduce the pharmacologic effects of Ketoconazole.

Sodium Iodide-I 131 interacts with Lithium
Avoid IODIDES in patients taking LITHIUM. Give Thyroid Hormone Supplements if hypothyroidism develops.
Resulting In: hypothyroidism Concomitant use of Lithium with Sodium Iodide 131 may act synergistically to produce hypothyroidism.

Sodium Salicylate interacts with Ethinyl Estradiol/Drosperinone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Drosperinone can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Ethynodiol Diacetate can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Levonorgestrel
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Levonorgestrel can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Norethindrone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norethindrone can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Norethindrone Acetate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norethindrone Acetate can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Norgestimate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norgestimate can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Ethinyl Estradiol/Norgestrel
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norgestrel can reduce the effectivness of Sodium Salicylate.

Sodium Salicylate interacts with Mestranol/Norethindrone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Mestranol/Norethindrone can reduce the effectivness of Sodium Salicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Drosperinone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Drosperinone can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Ethynodiol Diacetate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Ethynodiol Diacetate can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Levonorgestrel
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Levonorgestrel can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Norethindrone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norethindrone can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Norethindrone Acetate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norethindrone Acetate can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Norgestimate
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norgestimate can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Ethinyl Estradiol/Norgestrel
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Ethinyl Estradiol/Norgestrel can reduce the effectivness of Sodium Thiosalicylate.

Sodium Thiosalicylate interacts with Mestranol/Norethindrone
Monitor SALICYLATE level if maintenance of a specific concentration is important. May need a higher or more frequent SALICYLATE dose.
Mestranol/Norethindrone can reduce the effectivness of Sodium Thiosalicylate.

Succimer interacts with Edetate Calcium Disodium
Manufacturer does not recommend concomitant use of these agents.
Effects of combining Edetate Calcium Disodium and Succimer are unpredictable.

Sucralfate interacts with Warfarin Sodium
Monitor anticoagulation factors and adjust WARFARIN dose if needed. Separate administration time of this 2 agents by at least 2 hours.
Sucralfate can reduce the anticoagulant effects of Warfarin Sodium.

Sulfinpyrazone interacts with Warfarin Sodium
Monitor anticoagulation factors. Adjust WARFARIN dose when staring or stopping SULFINPYRAZONE.
Resulting In: hemorrhage Sulfinpyrazone can increase the anticoagulant effects of Warfarin Sodium.

Sulfisoxazole interacts with Thiopental Sodium
Reduce dose of THIOPENTAL in patient taking SULFISOXAZOLE.
Sulfisoxazole may increase the pharmacological effects of Thiopental Sodium.

Tamsulosin HCl interacts with Warfarin Sodium
Use this combination with caution.
Effects of combining Warfarin Sodium and Tamsulosin HCl are unpredictable.

Telmisartan interacts with Warfarin Sodium
Not clinically significant.
Telmisartan may reduce serum levels of Warfarin Sodium.

Teniposide interacts with Methotrexate Sodium
Not clinically significant.
Teniposide may increase the clearance of Methotrexate Sodium.

Teniposide interacts with Sodium Salicylate
Use this combination with caution.
Sodium Salicylate can increase the serum levels of Teniposide and increase the risk of toxicity.

Tetracycline HCl interacts with Methotrexate Sodium
Monitor METHOTREXATE level and watch for signs of toxicity.
Resulting In: myelosuppression Tetracycline HCl can increase the serum levels of Methotrexate and increase the risk of toxicity.

Thiopental Sodium interacts with Hydrocodone Bitartrate
No special precautions necessary, just routine monitoring in anesthesia.
Resulting In: Apnea Hydrocodone Bitartrate may increase the pharmacological effects of Thiopental Sodium.

Thiopental Sodium interacts with Ketamine
Monitor patient response and adjust THIOPENTAL dose as needed.
Ketamine may antagonize the hypnotic effects of Thiopental Sodium.

Thiopental Sodium interacts with Nalbuphine
No special precautions, just routine monitoring in anesthesia.
Resulting In: Apnea Nalbuphine may prolong the pharmacological effects of Thiopental Sodium.

Tiagabine interacts with Phenytoin Sodium, Prompt
Monitor drug levels and patient response.
Phenytoin may increase the clearance of Tiagabine.

Tiagabine interacts with Valproate Sodium
An increased risk of tiagabine adverse effects. Monitor for excessive adverse effects (dizziness, drowsiness, nausea, etc)
Concurrent use of Valproate Sodium and Tiagabine may reduce the protein binding of Tiagabine. Tiagabine may reduce serum levels of Valproate Sodium.

Tiludronate Disodium interacts with Aspirin
Separate the administration time as much as possible, at least 2 hours.
Aspirin may reduce bioavailability of Tiludronate Disodium.

Tiludronate Disodium interacts with Indomethacin
Seperate administration time of these drugs by at least 2 hours.
Concomitant use of Indomethacin and Tiludronate Disodium may increase the bioavailability of Tiludronate Disodium.

Tinzaparin Sodium interacts with Abciximab
Avoid this combination if possible.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Abciximab may increase the risk of bleeding.

Tinzaparin Sodium interacts with Anisindione
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Anisindione may increase the risk of bleeding.

Tinzaparin Sodium interacts with Danaparoid
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Danaparoid may increase the risk of bleeding.

Tinzaparin Sodium interacts with Dicumarol
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Dicumarol may increase the risk of bleeding.

Tinzaparin Sodium interacts with Dipyridamole
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Dipyridamole may increase the risk of bleeding.

Tinzaparin Sodium interacts with Ticlopidine HCl
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Ticlopidine HCl may increase the risk of bleeding.

Tinzaparin Sodium interacts with Warfarin Sodium
Use with caution. Monitor anticoagulant activity.
Resulting In: increased bleeding tendencies Co-administration of Tinzaparin Sodium and Warfarin Sodium may increase the risk of bleeding.

Tirofiban interacts with Heparin Sodium
Avoid this combination or use with caution.
Resulting In: increased bleeding tendencies Co-administration of Heparin Sodium and Tirofiban may increase the risk of bleeding.

Tirofiban interacts with Levothyroxine Sodium (T4)
Clinical significance unknown.
Levothyroxine Sodium may increase the clearance of Tirofiban.

Tolcapone interacts with Warfarin Sodium
Information for this interaction is limited. Monitor coagulation factors.
Tolcapone may reduce the clearance of Warfarin Sodium.

Tramadol/Acetaminophen interacts with Warfarin Sodium
Monitor PT and INR carefully.
Concomitant use of Tramadol/Acetaminophen and Warfarin Sodium may cause an increase in prothrombin time.

Trazodone HCl interacts with Phenytoin Sodium, Prompt
May need to lower PHENYTOIN dosage when using this combination. Monitor PHENYTOIN level and adjust dosage as needed.
Trazodone HCl may increase the serum levels and pharmacological and adverse effects of Phenytoin.

Trazodone HCl interacts with Warfarin Sodium
Monitor anticoagulation factors; may need to increase WARFARIN dose as needed.
Trazodone HCl can reduce the anticoagulant effects of Warfarin Sodium.

Trimethoprim interacts with Methotrexate Sodium
Avoid this combination if possible. Monitor for signs of hematologic toxicity. Leucovorin can be used for METHOTREXATE toxicity.
Resulting In: Megaloblastic anemia, bone marrow suppression Concomitant administartion of Trimethoprim and Methotrexate may increase the risk Methotrexate toxicity.

Typhoid Vaccine interacts with Phenytoin Sodium, Prompt
Monitor patient response. Patient may not be protected completely even after immunization.
Phenytoin can reduce the effectivness of Typhoid Vaccine.

Urokinase interacts with Heparin Sodium
Do not use HEPARIN with large dose of UROKINASE. Monitor patient closely.
Resulting In: hemorrhage Co-administration of Heparin Sodium and Urokinase may increase the risk of bleeding.

Verapamil HCl interacts with Dantrolene Sodium
Monitor potassium level and cardiac function. Can use an alternative to VERAPAMIL such as Nifedipine.
Resulting In: Hyperkalemia, myocardial depression Concomitant use of Dantrolene Sodium and Verapamil HCl can potentiate some adverse effects.

Vinblastine Sulfate interacts with Phenytoin Sodium, Prompt
Monitor serum PHENYTOIN level and adjust dosage as needed. Monitor effectiveness of therapy and adjust dose of VINBLASTINE and PHENYTOIN as needed.
Additive inhibitory effects and cytotoxicity by Phenytoin and Vinblastine combination. Vinblastine Sulfate can reduce the serum levels and the effectiveness of Phenytoin.

Vincristine Sulfate interacts with Phenytoin Sodium, Prompt
Monitor phenytoin levels and seizure activity. Adjust dose of either VINCRISTINE or PHENYTOIN as needed.
Additive cytotoxicity effects of Vincristine in combination with Phenytoin. Phenytoin may increase the clearance of Vincristine Sulfate. Vincristine Sulfate may reduce the serum levels and pharmacological effects of Phenytoin.

Warfarin Sodium interacts with Amiodarone HCl
Reduction in dose of ANTICOAGULANT is usually required (25 to 50% reduction is typical). Monitor anticoagulation factors closely (especially for the first 2 to 4 weeks of combined therapy) and adjust WARFARIN dose as needed. (The interaction can persists
Amiodarone HCl can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Celecoxib
Monitor INR/PT carefully when starting or stopping CELECOXIB therapy in combination with WARFARIN. Adjust WARFARIN dose as needed.
Resulting In: Hemorrhage Celecoxib can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Cimetidine
Avoid this drug combination if possible. Monitor anticoagulation factors if combination is used.
Resulting In: hemorrhage Cimetidine can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Cyclosporine
Monitor anticoagulant parameters, CYCLOSPORINE level and and patient response. Adjust the dose of either drugs as needed.
Effects of Warfarin Sodium and Cyclosporine may be decreased.

Warfarin Sodium interacts with Danazol
Monitor anticoagulation factors carefully and decrease dose of ANTICOAGULANT if necessary.
Danazol may increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Disulfiram
Monitor anticoagulant activity and adjust WARFARIN dose as needed.
Disulfiram may increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Dong Quai
Consult your health care provider before using herbal products. Monitor anticoagulant parameters and watch for signs of bleeding.
Dong Quai may increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Desogestrel
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Desogestrel may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Drosperinone
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Drosperinone may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Ethynodiol Diacetate
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Ethynodiol Diacetate may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Levonorgestrel
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Levonorgestrel may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Norethindrone
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Norethindrone may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Norethindrone Acetate
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Norethindrone Acetate may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Norgestimate
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Norgestimate may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Ethinyl Estradiol/Norgestrel
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Ethinyl Estradiol/Norgestrel may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Fluconazole
Monitor anticoagulation factors frequently when adding an AZOLE ANTIFUNGAL to WARFARIN. Adjust dose of ANTICOAGULANT as necessary.
Resulting In: increased bleeding tendencies Fluconazole can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Itraconazole
Monitor anticoagulation factors frequently when adding an AZOLE ANTIFUNGAL to WARFARIN. Adjust dose of ANTICOAGULANT as necessary.
Itraconazole can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Ketoconazole
Monitor anticoagulation factors frequently when adding an AZOLE ANTIFUNGAL to WARFARIN. Adjust dose of ANTICOAGULANT as necessary.
Ketoconazole can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Magnesium Salicylate
Avoid combining SALICYLATES with WARFARIN if possible. If the combination is necessary, monitor anticoagulation factors closely.
Magnesium Salicylate can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Mestranol/Norethindrone
ORAL CONTRACEPTIVES and high dose estrogens may be thrombogenic in rare occasions. No special precautions necessary. Monitor anticoagulation paremeters as usual.
Mestranol/Norethindrone may alter the therapeutic effects of Warfarin Sodium.

Warfarin Sodium interacts with Metronidazole
Monitor anticoagulation factors and adjust dose of ANTICOAGULANT if necessary.
Resulting In: hemorrhage Metronidazole can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Miconazole Nitrate
Monitor anticoagulation factors frequently when adding an AZOLE ANTIFUNGAL to WARFARIN. Adjust dose of ANTICOAGULANT as necessary.
Miconazole Nitrate can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Tinidazole
Monitor anticoagulation factors and adjust dose of ANTICOAGULANT if necessary, up to 8 days after discontinuation of tinidazole.
Resulting In: hemorrhage Tinidazole can increase the anticoagulant effects of Warfarin Sodium.

Warfarin Sodium interacts with Vitamin K
Monitor INR/PT carefully. Limit the amount of vitamin K ingested.
(High amounts of vitamin K can be found in GREEN TEA, BRUSSEL SPROUTS, KALE, ASPARAGUS, AVOCADO, BROCCOLI, CABBAGE, CAULIFLOWER, COLLARD GREENS, LIVER, SOYBEANS, MUSTARD GREENS, TURNIP GREENS, PEAS, PARSLEY, GREEN ONIONS, SPINACH, AND LETTUCE. Also be ca

Zafirlukast interacts with Warfarin Sodium
Monitor clotting time and adjust WARFARIN dose accordingly.
Resulting In: increased prothrombin time Zafirlukast may increase the anticoagulant effects of Warfarin Sodium.

Zalcitabine interacts with Phenytoin Sodium, Prompt
Avoid this combination if possible. Monitor renal function and adjust dosage as needed.
Resulting In: Peripheral neuropathy Concomitant use of Phenytoin and Zalcitabine may increase the risk of developing peripheral neuropathy.

Zileuton interacts with Warfarin Sodium
Monitor prothrombin time (PT) closely.
Resulting In: increased prothrombin time Zileuton may increase the anticoagulant effects of Warfarin Sodium.

Zonisamide interacts with Phenytoin Sodium, Prompt
Monitor patient response and drug levels; adjust dosage as needed.
Resulting In: P450 cytochrome enzyme induction effect Phenytoin may increase the metabolism of Zonisamide and decrease its serum concentration.

Sodium

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